Angiotensin-(1-7) inhibits vascular remodelling in rat jugular vein grafts via reduced ERK1/2 and p38 MAPK activity.

Wu, J-G; Tang, H; Liu, Z-J; Ma, Z-F; Tang, A-L; Zhang, X-J; Gao, X-R; Ma, H

Wu, J-G; Tang, H; Liu, Z-J; Ma, Z-F; Tang, A-L; Zhang, X-J; Gao, X-R; Ma, H.

Affiliation

Wu JG; Department of Cardiology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.

J Int Med Res ; 39(6): 2158-68, 2011.

Article in En | MEDLINE | ID: mdl-22289531

Subject(s)

Angiotensin I/pharmacology; Blood Vessel Prosthesis; Extracellular Signal-Regulated MAP Kinases/metabolism; Jugular Veins/enzymology; Jugular Veins/physiopathology; MAP Kinase Signaling System/drug effects; Peptide Fragments/pharmacology; p38 Mitogen-Activated Protein Kinases/metabolism; Actins/metabolism; Angiotensin I/administration & dosage; Angiotensin II/metabolism; Animals; Body Weight/drug effects; Enzyme Activation/drug effects; Hemodynamics/drug effects; Infusions, Intravenous; Jugular Veins/drug effects; Jugular Veins/pathology; Male; Mitogen-Activated Protein Kinase 1/metabolism; Mitogen-Activated Protein Kinase 3/metabolism; Peptide Fragments/administration & dosage; Proliferating Cell Nuclear Antigen/metabolism; Rats; Rats, Sprague-Dawley; Transplantation, Autologous

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Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / Angiotensin I / Blood Vessel Prosthesis / MAP Kinase Signaling System / Extracellular Signal-Regulated MAP Kinases / P38 Mitogen-Activated Protein Kinases / Jugular Veins Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Int Med Res Year: 2011 Document type: Article Affiliation country: China Country of publication: United kingdom

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