The ganglioside G(D2) induces the constitutive activation of c-Met in MDA-MB-231 breast cancer cells expressing the G(D3) synthase.

Cazet, Aurélie; Bobowski, Marie; Rombouts, Yoann; Lefebvre, Jonathan; Steenackers, Agata; Popa, Iuliana; Guérardel, Yann; Le Bourhis, Xuefen; Tulasne, David; Delannoy, Philippe

Cazet, Aurélie; Bobowski, Marie; Rombouts, Yoann; Lefebvre, Jonathan; Steenackers, Agata; Popa, Iuliana; Guérardel, Yann; Le Bourhis, Xuefen; Tulasne, David; Delannoy, Philippe.

Affiliation

Cazet A; Université Lille Nord de France, F-59000 Lille, France.

Glycobiology ; 22(6): 806-16, 2012 Jun.

Article in En | MEDLINE | ID: mdl-22301273

Subject(s)

Breast Neoplasms/metabolism; Gangliosides/metabolism; Proto-Oncogene Proteins c-met/metabolism; Sialyltransferases/genetics; Antibodies, Monoclonal/pharmacology; Breast Neoplasms/enzymology; Breast Neoplasms/pathology; Cell Membrane/chemistry; Cell Membrane/metabolism; Cell Proliferation/drug effects; Gangliosides/analysis; Humans; Mass Spectrometry; Phenotype; Phosphorylation/drug effects; Proto-Oncogene Proteins c-met/antagonists & inhibitors; RNA Interference; RNA, Small Interfering/genetics; RNA, Small Interfering/pharmacology; Sialyltransferases/metabolism; Tumor Cells, Cultured

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sialyltransferases / Breast Neoplasms / Proto-Oncogene Proteins c-met / Gangliosides Limits: Humans Language: En Journal: Glycobiology Journal subject: BIOQUIMICA Year: 2012 Document type: Article Affiliation country: France Country of publication: United kingdom

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