Chemically dimerized intravenous immunoglobulin has potent ameliorating activity in a mouse immune thrombocytopenic purpura model.

Machino, Yusuke; Suzuki, Emiko; Higurashi, Saki; Ohta, Hiroto; Suzuki, Mami; Kohroki, Junya; Masuho, Yasuhiko

Machino, Yusuke; Suzuki, Emiko; Higurashi, Saki; Ohta, Hiroto; Suzuki, Mami; Kohroki, Junya; Masuho, Yasuhiko.

Affiliation

Machino Y; Faculty of Pharmaceutical Sciences, Tokyo University of Science, Yamazaki 2641, Noda, Chiba 278-8510, Japan. yusuke.machino@kyowa-kirin.co.jp

Biochem Biophys Res Commun ; 418(4): 748-53, 2012 Feb 24.

Article in En | MEDLINE | ID: mdl-22306012

Subject(s)

Immunoglobulins, Intravenous/administration & dosage; Immunoglobulins, Intravenous/chemistry; Immunologic Factors/administration & dosage; Immunologic Factors/chemistry; Purpura, Thrombocytopenic/therapy; Animals; Antigens/immunology; Cross-Linking Reagents/chemistry; Disease Models, Animal; Immunoglobulins, Intravenous/immunology; Immunologic Factors/immunology; Male; Mice; Mice, Inbred BALB C; Protein Multimerization; Receptors, IgG/chemistry; Receptors, IgG/immunology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Purpura, Thrombocytopenic / Immunoglobulins, Intravenous / Immunologic Factors Type of study: Prognostic_studies Limits: Animals Language: En Journal: Biochem Biophys Res Commun Year: 2012 Document type: Article Affiliation country: Japan Country of publication: United States

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