Importance of pharmacokinetic profile and timing of coadministration of short- and long-acting formulations of methylphenidate on patterns of subjective responses and abuse potential.

Spencer, Thomas J; Biederman, Joseph; Martin, Jessica M; Moorehead, Tara McDonnell; Mirto, Tara; Clarke, Allison; Batchelder, Holly; Faraone, Stephen V

Spencer, Thomas J; Biederman, Joseph; Martin, Jessica M; Moorehead, Tara McDonnell; Mirto, Tara; Clarke, Allison; Batchelder, Holly; Faraone, Stephen V.

Affiliation

Spencer TJ; Massachusetts General Hospital, Boston, MA 02114, USA. tspencer@partners.org

Postgrad Med ; 124(1): 166-73, 2012 Jan.

Article in En | MEDLINE | ID: mdl-22314126

Subject(s)

Central Nervous System Stimulants/administration & dosage; Methylphenidate/administration & dosage; Substance-Related Disorders/prevention & control; Adolescent; Adult; Attitude; Central Nervous System Stimulants/blood; Central Nervous System Stimulants/pharmacokinetics; Cross-Over Studies; Delayed-Action Preparations; Double-Blind Method; Drug Administration Schedule; Female; Humans; Linear Models; Male; Methylphenidate/blood; Methylphenidate/pharmacokinetics; Middle Aged; Substance-Related Disorders/psychology; Surveys and Questionnaires; Young Adult

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Substance-Related Disorders / Central Nervous System Stimulants / Methylphenidate Type of study: Clinical_trials Limits: Adolescent / Adult / Female / Humans / Male / Middle aged Language: En Journal: Postgrad Med Year: 2012 Document type: Article Affiliation country: United States Country of publication: United kingdom

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