11q23 rearrangement and duplication of MLLT1-MLL gene fusion in therapy-related acute myeloid leukemia.

Chin, Loi-Khim; Cheah, Chan Y; Michael, Patricia M; MacKinnon, Ruth N; Campbell, Lynda J

Chin, Loi-Khim; Cheah, Chan Y; Michael, Patricia M; MacKinnon, Ruth N; Campbell, Lynda J.

Leuk Lymphoma ; 53(10): 2066-8, 2012 Oct.

Article in En | MEDLINE | ID: mdl-22335556

Subject(s)

Chromosomes, Human, Pair 11; Gene Duplication; Leukemia, Myeloid, Acute/genetics; Myeloid-Lymphoid Leukemia Protein/genetics; Neoplasm Proteins/genetics; Nuclear Proteins/genetics; Oncogene Proteins, Fusion/genetics; Transcription Factors/genetics; Translocation, Genetic; Azathioprine/adverse effects; Azathioprine/therapeutic use; Chromosome Banding; Cyclosporine/adverse effects; Cyclosporine/therapeutic use; Female; Hepatitis, Autoimmune/drug therapy; Histone-Lysine N-Methyltransferase; Humans; Immunosuppressive Agents/adverse effects; Immunosuppressive Agents/therapeutic use; In Situ Hybridization, Fluorescence; Leukemia, Myeloid, Acute/chemically induced; Young Adult

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Translocation, Genetic / Chromosomes, Human, Pair 11 / Nuclear Proteins / Leukemia, Myeloid, Acute / Oncogene Proteins, Fusion / Gene Duplication / Myeloid-Lymphoid Leukemia Protein / Neoplasm Proteins Limits: Adult / Female / Humans Language: En Journal: Leuk Lymphoma Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2012 Document type: Article

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