Synthesis of ApoSense compound [18F]2-(5-(dimethylamino)naphthalene-1-sulfonamido)-2-(fluoromethyl)butanoic acid ([18F]NST732) by nucleophilic ring opening of an aziridine precursor.

Basuli, Falguni; Wu, Haitao; Shi, Zhen-Dan; Teng, Bao; Li, Changhui; Sulima, Agnieszka; Bate, Aaron; Young, Philip; McMillan, Mathew; Griffiths, Gary L

Basuli, Falguni; Wu, Haitao; Shi, Zhen-Dan; Teng, Bao; Li, Changhui; Sulima, Agnieszka; Bate, Aaron; Young, Philip; McMillan, Mathew; Griffiths, Gary L.

Affiliation

Basuli F; Imaging Probe Development Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Rockville, MD 20850, USA. bhattacharyyaf@mail.nih.gov

Nucl Med Biol ; 39(5): 687-96, 2012 Jul.

Article in En | MEDLINE | ID: mdl-22336374

Subject(s)

Aminobutyrates/chemistry; Aminobutyrates/chemical synthesis; Aziridines/chemistry; Butyric Acid/chemistry; Butyric Acid/chemical synthesis; Chemistry Techniques, Synthetic/methods; Sulfonamides/chemistry; Sulfonamides/chemical synthesis; Chemistry Techniques, Synthetic/standards; Radiochemistry; Reference Standards

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfonamides / Aziridines / Butyric Acid / Chemistry Techniques, Synthetic / Aminobutyrates Language: En Journal: Nucl Med Biol Journal subject: BIOLOGIA / MEDICINA NUCLEAR Year: 2012 Document type: Article Affiliation country: United States Country of publication: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google