Annexin A5 prevents post-interventional accelerated atherosclerosis development in a dose-dependent fashion in mice.

Ewing, M M; Karper, J C; Sampietro, M L; de Vries, M R; Pettersson, K; Jukema, J W; Quax, P H A

Ewing, M M; Karper, J C; Sampietro, M L; de Vries, M R; Pettersson, K; Jukema, J W; Quax, P H A.

Affiliation

Ewing MM; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.

Atherosclerosis ; 221(2): 333-40, 2012 Apr.

Article in En | MEDLINE | ID: mdl-22341596

Subject(s)

Annexin A5/administration & dosage; Arterial Occlusive Diseases/prevention & control; Femoral Artery/drug effects; Animals; Annexin A5/genetics; Apolipoproteins E/deficiency; Apolipoproteins E/genetics; Arterial Occlusive Diseases/etiology; Arterial Occlusive Diseases/immunology; Arterial Occlusive Diseases/pathology; Case-Control Studies; Chemotaxis, Leukocyte/drug effects; Constriction; Constriction, Pathologic; Coronary Restenosis/genetics; Disease Models, Animal; Dose-Response Relationship, Drug; Endoplasmic Reticulum Chaperone BiP; Femoral Artery/pathology; Femoral Artery/surgery; Genetic Predisposition to Disease; Genome-Wide Association Study; Humans; Injections, Intraperitoneal; Mice; Mice, Inbred C57BL; Mice, Knockout; Netherlands; Odds Ratio; Polymorphism, Single Nucleotide; Risk Assessment; Risk Factors; Time Factors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arterial Occlusive Diseases / Annexin A5 / Femoral Artery Type of study: Clinical_trials / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Country/Region as subject: Europa Language: En Journal: Atherosclerosis Year: 2012 Document type: Article Affiliation country: Netherlands Country of publication: Ireland

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