Screening for fetal aneuploidy: is maternal age relevant?
Clin Obstet Gynecol
; 55(1): 217-25, 2012 Mar.
Article
in En
| MEDLINE
| ID: mdl-22343240
ABSTRACT
The process of genetic screening has evolved from a simple notation of maternal age to a complex algorithm incorporating age, maternal serum screening, and sonographic findings. The extent to which each of these variables should contribute to the overall screening result is much debated and deserves continued research. It is clear that maternal age provides useful information when used as part of this equation but should not represent the sole screening modality. The use of genetic screening in a general population should be examined in terms of cost effectiveness without sacrificing patient preference and autonomy.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Genetic Testing
/
Ultrasonography, Prenatal
/
Maternal Age
/
Down Syndrome
/
Aneuploidy
Type of study:
Diagnostic_studies
/
Prognostic_studies
/
Screening_studies
Limits:
Female
/
Humans
/
Pregnancy
Language:
En
Journal:
Clin Obstet Gynecol
Year:
2012
Document type:
Article
Affiliation country:
United States