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T-type calcium channel blockers that attenuate thalamic burst firing and suppress absence seizures.
Tringham, Elizabeth; Powell, Kim L; Cain, Stuart M; Kuplast, Kristy; Mezeyova, Janette; Weerapura, Manjula; Eduljee, Cyrus; Jiang, Xinpo; Smith, Paula; Morrison, Jerrie-Lynn; Jones, Nigel C; Braine, Emma; Rind, Gil; Fee-Maki, Molly; Parker, David; Pajouhesh, Hassan; Parmar, Manjeet; O'Brien, Terence J; Snutch, Terrance P.
Affiliation
  • Tringham E; Zalicus Pharmaceuticals Ltd., Suite 301, 2389 Health Sciences Mall, Vancouver, British Columbia V6T 1Z3, Canada.
Sci Transl Med ; 4(121): 121ra19, 2012 Feb 15.
Article in En | MEDLINE | ID: mdl-22344687
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thalamus / Benzamides / Calcium Channel Blockers / Epilepsy, Absence / Calcium Channels, T-Type / Acetamides Limits: Humans Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2012 Document type: Article Affiliation country: Canada Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thalamus / Benzamides / Calcium Channel Blockers / Epilepsy, Absence / Calcium Channels, T-Type / Acetamides Limits: Humans Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2012 Document type: Article Affiliation country: Canada Country of publication: United States