Cyclodextrin-based iminosugar click clusters: the first examples of multivalent pharmacological chaperones for the treatment of lysosomal storage disorders.

Decroocq, Camille; Rodríguez-Lucena, David; Ikeda, Kyoko; Asano, Naoki; Compain, Philippe

Decroocq, Camille; Rodríguez-Lucena, David; Ikeda, Kyoko; Asano, Naoki; Compain, Philippe.

Affiliation

Decroocq C; Laboratoire de Synthèse Organique et Molécules Bioactives, Université de Strasbourg/CNRS (UMR 7509), Ecole Européenne de Chimie, Polymères et Matériaux, 25 rue Becquerel, 67087 Strasbourg, France.

Chembiochem ; 13(5): 661-4, 2012 Mar 19.

Article in En | MEDLINE | ID: mdl-22344719

Subject(s)

Cyclodextrins/therapeutic use; Imino Sugars/therapeutic use; Lysosomal Storage Diseases/drug therapy; Molecular Chaperones/therapeutic use; Click Chemistry; Cyclodextrins/chemistry; Cyclodextrins/pharmacology; Humans; Imino Sugars/chemistry; Imino Sugars/pharmacology; Molecular Chaperones/chemistry; Molecular Chaperones/pharmacology; Molecular Structure

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lysosomal Storage Diseases / Molecular Chaperones / Cyclodextrins / Imino Sugars Limits: Humans Language: En Journal: Chembiochem Journal subject: BIOQUIMICA Year: 2012 Document type: Article Affiliation country: France

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