The effect of systemic corticosteroid therapy on the expression of toll-like receptor 2 and toll-like receptor 4 in the cutaneous lesions of leprosy Type 1 reactions.

Walker, S L; Roberts, C H; Atkinson, S E; Khadge, S; Macdonald, M; Neupane, K D; Ranjit, C; Sapkota, B R; Dhakal, S; Hawksworth, R A; Mahat, K; Ruchal, S; Hamal, S; Hagge, D A; Lockwood, D N J

Walker, S L; Roberts, C H; Atkinson, S E; Khadge, S; Macdonald, M; Neupane, K D; Ranjit, C; Sapkota, B R; Dhakal, S; Hawksworth, R A; Mahat, K; Ruchal, S; Hamal, S; Hagge, D A; Lockwood, D N J.

Affiliation

Walker SL; Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK. drstevewalker@hotmail.com

Br J Dermatol ; 167(1): 29-35, 2012 Jul.

Article in En | MEDLINE | ID: mdl-22348338

Subject(s)

Glucocorticoids/therapeutic use; Leprosy/drug therapy; Toll-Like Receptor 2/physiology; Toll-Like Receptor 4/physiology; Adolescent; Adult; Analysis of Variance; Antibiotics, Antitubercular/therapeutic use; DNA, Complementary/biosynthesis; Drug Therapy, Combination; Female; Gene Expression; Humans; Immunohistochemistry; Leprosy/genetics; Leprosy/mortality; Male; Methylprednisolone/therapeutic use; Middle Aged; Prednisolone/therapeutic use; Toll-Like Receptor 2/drug effects; Toll-Like Receptor 2/genetics; Toll-Like Receptor 2/metabolism; Toll-Like Receptor 4/drug effects; Toll-Like Receptor 4/genetics; Toll-Like Receptor 4/metabolism; Young Adult

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Toll-Like Receptor 2 / Toll-Like Receptor 4 / Glucocorticoids / Leprosy Type of study: Clinical_trials Limits: Adolescent / Adult / Female / Humans / Male / Middle aged Language: En Journal: Br J Dermatol Year: 2012 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom

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