Requirements for efficient proteolytic cleavage of prelamin A by ZMPSTE24.

Barrowman, Jemima; Hamblet, Corinne; Kane, Megan S; Michaelis, Susan

Barrowman, Jemima; Hamblet, Corinne; Kane, Megan S; Michaelis, Susan.

Affiliation

Barrowman J; Department of Cell Biology, The Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America.

PLoS One ; 7(2): e32120, 2012.

Article in En | MEDLINE | ID: mdl-22355414

Subject(s)

Cell Nucleus/metabolism; Membrane Proteins/physiology; Metalloendopeptidases/physiology; Nuclear Proteins/metabolism; Protein Precursors/metabolism; Protein Prenylation; Proteolysis; Aging, Premature; Amino Acid Sequence; Animals; Blotting, Western; Cells, Cultured; Fibroblasts/cytology; Fibroblasts/metabolism; Humans; Kidney/cytology; Kidney/metabolism; Lamin Type A; Mice; Mice, Knockout; Molecular Sequence Data; Mutation/genetics; Plasmids/genetics; Sequence Homology, Amino Acid

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Precursors / Metalloendopeptidases / Nuclear Proteins / Cell Nucleus / Protein Prenylation / Proteolysis / Membrane Proteins Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2012 Document type: Article Affiliation country: United States

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