Effects of exposure to low-level lead on spatial learning and memory and the expression of mGluR1, NMDA receptor in different developmental stages of rats.

Wang, Xin-Mei; Liu, Wen-Jun; Zhang, Rong; Zhou, Yi-Kai

Wang, Xin-Mei; Liu, Wen-Jun; Zhang, Rong; Zhou, Yi-Kai.

Affiliation

Wang XM; MOE Key Laboratory of Environment and Health, Institute of Environmental Medicine, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, PR China.

Toxicol Ind Health ; 29(8): 686-96, 2013 Sep.

Article in En | MEDLINE | ID: mdl-22362014

Subject(s)

Lead/toxicity; Maze Learning/drug effects; Memory/drug effects; Receptors, Metabotropic Glutamate/metabolism; Receptors, N-Methyl-D-Aspartate/metabolism; Animals; Cerebral Cortex/drug effects; Cerebral Cortex/metabolism; Female; Gene Expression Regulation; Hippocampus/drug effects; Hippocampus/metabolism; Lactation/drug effects; Male; Memory Disorders/chemically induced; Memory Disorders/pathology; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate/genetics; Receptors, N-Methyl-D-Aspartate/genetics

Key words

Lead; NMDA; learning and memory; mGluR1; neurotoxicity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, N-Methyl-D-Aspartate / Receptors, Metabotropic Glutamate / Maze Learning / Lead / Memory Limits: Animals / Pregnancy Language: En Journal: Toxicol Ind Health Journal subject: MEDICINA OCUPACIONAL / TOXICOLOGIA Year: 2013 Document type: Article Country of publication: United kingdom

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