Neonatal periostin knockout mice are protected from hyperoxia-induced alveolar simplication.

Bozyk, Paul D; Bentley, J Kelley; Popova, Antonia P; Anyanwu, Anuli C; Linn, Marisa D; Goldsmith, Adam M; Pryhuber, Gloria S; Moore, Bethany B; Hershenson, Marc B

Bozyk, Paul D; Bentley, J Kelley; Popova, Antonia P; Anyanwu, Anuli C; Linn, Marisa D; Goldsmith, Adam M; Pryhuber, Gloria S; Moore, Bethany B; Hershenson, Marc B.

Affiliation

Bozyk PD; Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, United States of America.

PLoS One ; 7(2): e31336, 2012.

Article in En | MEDLINE | ID: mdl-22363622

Subject(s)

Cell Adhesion Molecules/deficiency; Hyperoxia/pathology; Hyperoxia/prevention & control; Pulmonary Alveoli/pathology; Aged; Aged, 80 and over; Animals; Animals, Newborn; Bronchopulmonary Dysplasia/complications; Bronchopulmonary Dysplasia/metabolism; Bronchopulmonary Dysplasia/pathology; Cell Adhesion Molecules/genetics; Cell Adhesion Molecules/metabolism; Cell Differentiation/drug effects; DNA/biosynthesis; Female; Gene Expression Regulation, Developmental/drug effects; Gene Knockout Techniques; Humans; Hyperoxia/complications; Hyperoxia/genetics; Hypoventilation/complications; Hypoventilation/metabolism; Hypoventilation/pathology; Infant, Newborn; Male; Mesenchymal Stem Cells/drug effects; Mesenchymal Stem Cells/metabolism; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Myofibroblasts/drug effects; Myofibroblasts/metabolism; Myofibroblasts/pathology; Phenotype; Pulmonary Alveoli/drug effects; Pulmonary Alveoli/growth & development; Pulmonary Alveoli/metabolism; RNA, Messenger/genetics; RNA, Messenger/metabolism; Transforming Growth Factor beta/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pulmonary Alveoli / Cell Adhesion Molecules / Hyperoxia Type of study: Prognostic_studies Limits: Aged80 Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2012 Document type: Article Affiliation country: United States Country of publication: United States

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