Use of a polyanionic carbomer, Carbopol971P, in combination with MF59, improves antibody responses to HIV-1 envelope glycoprotein.

Dey, Antu K; Burke, Brian; Sun, Yide; Hartog, Karin; Heeney, Jonathan L; Montefiori, David; Srivastava, Indresh K; Barnett, Susan W

Dey, Antu K; Burke, Brian; Sun, Yide; Hartog, Karin; Heeney, Jonathan L; Montefiori, David; Srivastava, Indresh K; Barnett, Susan W.

Affiliation

Dey AK; Novartis Vaccines & Diagnostics, 45 Sidney Street, Cambridge, MA 02139, USA. antu.dey@novartis.com

Vaccine ; 30(17): 2749-59, 2012 Apr 05.

Article in En | MEDLINE | ID: mdl-22366638

Subject(s)

AIDS Vaccines/immunology; Acrylates/administration & dosage; Adjuvants, Immunologic/administration & dosage; HIV Antibodies/blood; HIV-1/immunology; Polysorbates/administration & dosage; Squalene/administration & dosage; env Gene Products, Human Immunodeficiency Virus/immunology; AIDS Vaccines/administration & dosage; AIDS Vaccines/adverse effects; Acrylates/adverse effects; Acrylates/metabolism; Adjuvants, Immunologic/adverse effects; Animals; Antibodies, Neutralizing/immunology; Female; HIV Antibodies/immunology; Humans; Hydrogen-Ion Concentration; Polysorbates/adverse effects; Protein Binding; Protein Stability; Rabbits; Squalene/adverse effects; env Gene Products, Human Immunodeficiency Virus/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polysorbates / Squalene / Acrylates / HIV Antibodies / Adjuvants, Immunologic / HIV-1 / AIDS Vaccines / Env Gene Products, Human Immunodeficiency Virus Limits: Animals / Female / Humans Language: En Journal: Vaccine Year: 2012 Document type: Article Affiliation country: United States Country of publication: Netherlands

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