Adenosine A(2A) receptor blockade reverts hippocampal stress-induced deficits and restores corticosterone circadian oscillation.

Batalha, V L; Pego, J M; Fontinha, B M; Costenla, A R; Valadas, J S; Baqi, Y; Radjainia, H; Müller, C E; Sebastião, A M; Lopes, L V

Batalha, V L; Pego, J M; Fontinha, B M; Costenla, A R; Valadas, J S; Baqi, Y; Radjainia, H; Müller, C E; Sebastião, A M; Lopes, L V.

Affiliation

Batalha VL; Institute of Pharmacology and Neurosciences, Neurosciences Unit, Instituto de Medicina Molecular, Faculty of Medicine, University of Lisbon, Lisbon, Portugal.

Mol Psychiatry ; 18(3): 320-31, 2013 Mar.

Article in En | MEDLINE | ID: mdl-22371048

Subject(s)

Adenosine A2 Receptor Antagonists/pharmacology; Circadian Rhythm/physiology; Corticosterone/blood; Hippocampus/drug effects; Maze Learning/physiology; Receptor, Adenosine A2A/physiology; Stress, Psychological/physiopathology; Animals; Circadian Rhythm/drug effects; Dendrites/ultrastructure; Excitatory Postsynaptic Potentials/drug effects; Excitatory Postsynaptic Potentials/physiology; Female; Hippocampus/metabolism; Male; Maternal Deprivation; Maze Learning/drug effects; Neuronal Plasticity/drug effects; Neuronal Plasticity/physiology; Purines/pharmacology; Rats; Receptors, Glucocorticoid/metabolism; Stress, Psychological/drug therapy; Stress, Psychological/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stress, Psychological / Corticosterone / Circadian Rhythm / Maze Learning / Receptor, Adenosine A2A / Adenosine A2 Receptor Antagonists / Hippocampus Type of study: Prognostic_studies Limits: Animals Language: En Journal: Mol Psychiatry Journal subject: BIOLOGIA MOLECULAR / PSIQUIATRIA Year: 2013 Document type: Article Affiliation country: Portugal Country of publication: United kingdom

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