Preferential replication of systemically delivered oncolytic vaccinia virus in focally irradiated glioma xenografts.

Advani, Sunil J; Buckel, Lisa; Chen, Nanhai G; Scanderbeg, Daniel J; Geissinger, Ulrike; Zhang, Qian; Yu, Yong A; Aguilar, Richard J; Mundt, Arno J; Szalay, Aladar A

Advani, Sunil J; Buckel, Lisa; Chen, Nanhai G; Scanderbeg, Daniel J; Geissinger, Ulrike; Zhang, Qian; Yu, Yong A; Aguilar, Richard J; Mundt, Arno J; Szalay, Aladar A.

Affiliation

Advani SJ; Department of Radiation Medicine and Applied Sciences and Center for Advanced Radiotherapy Technologies, University of California San Diego, La Jolla, California 92093, USA. sjadvani@ucsd.edu

Clin Cancer Res ; 18(9): 2579-90, 2012 May 01.

Article in En | MEDLINE | ID: mdl-22379115

Subject(s)

Brain Neoplasms/therapy; Glioma/therapy; Oncolytic Virotherapy; Radiation, Ionizing; Vaccinia/therapy; Virus Replication; Animals; Brain Neoplasms/genetics; Brain Neoplasms/mortality; Cells, Cultured; Chlorocebus aethiops; Combined Modality Therapy; Fibroblasts/cytology; Fibroblasts/metabolism; Fibroblasts/radiation effects; Glioma/genetics; Glioma/mortality; Kidney/cytology; Kidney/metabolism; Kidney/radiation effects; Male; Mice; Mice, Nude; Survival Rate; Vaccinia/genetics; Vaccinia/mortality; Vaccinia virus/genetics; Xenograft Model Antitumor Assays

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Radiation, Ionizing / Vaccinia / Virus Replication / Brain Neoplasms / Oncolytic Virotherapy / Glioma Type of study: Prognostic_studies Limits: Animals Language: En Journal: Clin Cancer Res Journal subject: NEOPLASIAS Year: 2012 Document type: Article Affiliation country: United States Country of publication: United States

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