Interleukin-22 drives endogenous thymic regeneration in mice.

Dudakov, Jarrod A; Hanash, Alan M; Jenq, Robert R; Young, Lauren F; Ghosh, Arnab; Singer, Natalie V; West, Mallory L; Smith, Odette M; Holland, Amanda M; Tsai, Jennifer J; Boyd, Richard L; van den Brink, Marcel R M

Dudakov, Jarrod A; Hanash, Alan M; Jenq, Robert R; Young, Lauren F; Ghosh, Arnab; Singer, Natalie V; West, Mallory L; Smith, Odette M; Holland, Amanda M; Tsai, Jennifer J; Boyd, Richard L; van den Brink, Marcel R M.

Affiliation

Dudakov JA; Immunology Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA. dudakovj@mskcc.org

Science ; 336(6077): 91-5, 2012 Apr 06.

Article in En | MEDLINE | ID: mdl-22383805

Subject(s)

Interleukins/metabolism; Regeneration; Thymocytes/physiology; Thymus Gland/physiology; Animals; Cell Count; Cell Proliferation; Cell Survival; Dendritic Cells/physiology; Epithelial Cells/cytology; Epithelial Cells/physiology; Interleukin-23/metabolism; Interleukins/administration & dosage; Interleukins/deficiency; Interleukins/genetics; Lymphocytes/cytology; Lymphocytes/physiology; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nuclear Receptor Subfamily 1, Group F, Member 3/genetics; Nuclear Receptor Subfamily 1, Group F, Member 3/metabolism; Radiation Dosage; Receptors, Interleukin/metabolism; Recombinant Proteins/administration & dosage; Signal Transduction; Thymus Gland/cytology; Thymus Gland/immunology; Thymus Gland/radiation effects; Up-Regulation; Whole-Body Irradiation; Interleukin-22

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Regeneration / Thymus Gland / Interleukins / Thymocytes Limits: Animals Language: En Journal: Science Year: 2012 Document type: Article Affiliation country: United States Country of publication: United States

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