Poly(ADP-ribose) polymerase-1 inhibition by arsenite promotes the survival of cells with unrepaired DNA lesions induced by UV exposure.

Qin, Xu-Jun; Liu, Wenlan; Li, Ying-Na; Sun, Xi; Hai, Chun-Xu; Hudson, Laurie G; Liu, Ke Jian

Qin, Xu-Jun; Liu, Wenlan; Li, Ying-Na; Sun, Xi; Hai, Chun-Xu; Hudson, Laurie G; Liu, Ke Jian.

Affiliation

Qin XJ; Department of Pharmaceutical Sciences, College of Pharmacy, University of New Mexico, Albuquerque, New Mexico 87131-0001, USA.

Toxicol Sci ; 127(1): 120-9, 2012 May.

Article in En | MEDLINE | ID: mdl-22387748

Subject(s)

Arsenites/toxicity; DNA Damage/drug effects; DNA Repair/drug effects; Enzyme Inhibitors/toxicity; Poly(ADP-ribose) Polymerase Inhibitors; Ultraviolet Rays/adverse effects; Apoptosis/drug effects; Apoptosis/radiation effects; Caspase Inhibitors; Cell Line, Transformed; Cell Survival/drug effects; Dose-Response Relationship, Drug; Gene Knockdown Techniques; Gene Silencing; Humans; Keratinocytes/drug effects; Keratinocytes/radiation effects; Poly (ADP-Ribose) Polymerase-1; Radiation Effects

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ultraviolet Rays / DNA Damage / Arsenites / DNA Repair / Enzyme Inhibitors / Poly(ADP-ribose) Polymerase Inhibitors Type of study: Prognostic_studies Limits: Humans Language: En Journal: Toxicol Sci Journal subject: TOXICOLOGIA Year: 2012 Document type: Article Affiliation country: United States Country of publication: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google