Favorable survival maintained in children who have myeloid leukemia associated with Down syndrome using reduced-dose chemotherapy on Children's Oncology Group trial A2971: a report from the Children's Oncology Group.

Sorrell, April D; Alonzo, Todd A; Hilden, Joanne M; Gerbing, Robert B; Loew, Thomas W; Hathaway, Lois; Barnard, Dorothy; Taub, Jeffrey W; Ravindranath, Yaddanapudi; Smith, Franklin O; Arceci, Robert J; Woods, William G; Gamis, Alan S

Sorrell, April D; Alonzo, Todd A; Hilden, Joanne M; Gerbing, Robert B; Loew, Thomas W; Hathaway, Lois; Barnard, Dorothy; Taub, Jeffrey W; Ravindranath, Yaddanapudi; Smith, Franklin O; Arceci, Robert J; Woods, William G; Gamis, Alan S.

Affiliation

Sorrell AD; Department of Pediatrics, City of Hope National Medical Center, Duarte California, USA. asorrell@coh.org

Cancer ; 118(19): 4806-14, 2012 Oct 01.

Article in En | MEDLINE | ID: mdl-22392565

Subject(s)

Antineoplastic Combined Chemotherapy Protocols/administration & dosage; Down Syndrome/complications; Leukemia, Myeloid/drug therapy; Adolescent; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine/administration & dosage; Daunorubicin/administration & dosage; Dexamethasone/administration & dosage; Disease-Free Survival; Drug Administration Schedule; Etoposide/administration & dosage; Female; Humans; Infant; Kaplan-Meier Estimate; Leukemia, Myeloid/complications; Leukemia, Myeloid/surgery; Male; Thioguanine/administration & dosage; Treatment Outcome

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antineoplastic Combined Chemotherapy Protocols / Leukemia, Myeloid / Down Syndrome Type of study: Clinical_trials / Risk_factors_studies Limits: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male Language: En Journal: Cancer Year: 2012 Document type: Article Affiliation country: United States Country of publication: United States

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