Scabronine M, a novel inhibitor of NGF-induced neurite outgrowth from PC12 cells from the fungus Sarcodon scabrosus.

Liu, Li; Shi, Xin-Wei; Zong, Shi-Chun; Tang, Jiang-Jiang; Gao, Jin-Ming

Liu, Li; Shi, Xin-Wei; Zong, Shi-Chun; Tang, Jiang-Jiang; Gao, Jin-Ming.

Affiliation

Liu L; Shaanxi Engineering Center of Bioresource Chemistry & Sustainable Utilization, College of Science, Northwest A&F University, Yangling 712100, Shaanxi, China.

Bioorg Med Chem Lett ; 22(7): 2401-6, 2012 Apr 01.

Article in En | MEDLINE | ID: mdl-22401866

Subject(s)

Basidiomycota/chemistry; Diterpenes/isolation & purification; Fruiting Bodies, Fungal/chemistry; Nerve Growth Factors/antagonists & inhibitors; Neurites/drug effects; Animals; Diterpenes/chemistry; Diterpenes/pharmacology; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases/antagonists & inhibitors; Magnetic Resonance Spectroscopy; Molecular Structure; Nerve Growth Factors/pharmacology; Neurites/physiology; PC12 Cells; Phosphorylation/drug effects; Rats

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Basidiomycota / Neurites / Fruiting Bodies, Fungal / Diterpenes / Nerve Growth Factors Limits: Animals Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2012 Document type: Article Affiliation country: China Country of publication: United kingdom

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