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Association of the intronic polymorphism rs891512 (G24943A) of the endothelial nitric oxide synthase gene with hypertension in Chilean type 2 diabetes patients.
Seelenfreund, D; Lobos, S R; Quesada, A; Saavedra, J M; Wolff, C; López-Stewart, G; Araya, A V; Durruty, P.
Affiliation
  • Seelenfreund D; Department of Biochemistry, Faculty of Chemical and Pharmaceutical Sciences, University of Chile, V. Mackenna 20, Providencia, Santiago, Chile. dseelen@ciq.uchile.cl
Diabetes Res Clin Pract ; 96(2): e47-9, 2012 May.
Article in En | MEDLINE | ID: mdl-22425436
ABSTRACT
We investigated two single nucleotide polymorphisms of the NOS3 gene in type 2 diabetic patients (n=93) and healthy non-diabetic controls (n=76) and their relationship with smoking habits, body mass index, hypertension and dyslipidemia. Results showed that eNOS polymorphism rs891512 (G24943A) is associated with hypertension in Chilean individuals (p<0.05).
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polymorphism, Single Nucleotide / Diabetes Mellitus, Type 2 / Nitric Oxide Synthase Type III / Hypertension Type of study: Risk_factors_studies Limits: Humans Country/Region as subject: America do sul / Chile Language: En Journal: Diabetes Res Clin Pract Journal subject: ENDOCRINOLOGIA Year: 2012 Document type: Article Affiliation country: Chile
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polymorphism, Single Nucleotide / Diabetes Mellitus, Type 2 / Nitric Oxide Synthase Type III / Hypertension Type of study: Risk_factors_studies Limits: Humans Country/Region as subject: America do sul / Chile Language: En Journal: Diabetes Res Clin Pract Journal subject: ENDOCRINOLOGIA Year: 2012 Document type: Article Affiliation country: Chile