Phenotypic effects of repeated psychosocial stress during adolescence in mice mutant for the schizophrenia risk gene neuregulin-1: a putative model of gene × environment interaction.

Desbonnet, Lieve; O'Tuathaigh, Colm; Clarke, Gerard; O'Leary, Claire; Petit, Emilie; Clarke, Niamh; Tighe, Orna; Lai, Donna; Harvey, Richard; Cryan, John F; Dinan, Timothy G; Waddington, John L

Desbonnet, Lieve; O'Tuathaigh, Colm; Clarke, Gerard; O'Leary, Claire; Petit, Emilie; Clarke, Niamh; Tighe, Orna; Lai, Donna; Harvey, Richard; Cryan, John F; Dinan, Timothy G; Waddington, John L.

Affiliation

Desbonnet L; Molecular & Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin 2, Ireland. lievedesbonnet@rcsi.ie

Brain Behav Immun ; 26(4): 660-71, 2012 May.

Article in En | MEDLINE | ID: mdl-22426432

Subject(s)

Gene-Environment Interaction; Neuregulin-1/genetics; Schizophrenia/genetics; Schizophrenic Psychology; Stress, Psychological/genetics; Animals; Brain-Derived Neurotrophic Factor/analysis; Corticosterone/analysis; Cytokines/analysis; Disease Models, Animal; Environment; Exploratory Behavior; Genotype; Mice; Mice, Knockout; Phenotype; Social Behavior

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Schizophrenia / Schizophrenic Psychology / Stress, Psychological / Neuregulin-1 / Gene-Environment Interaction Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: Brain Behav Immun Journal subject: ALERGIA E IMUNOLOGIA / CEREBRO / PSICOFISIOLOGIA Year: 2012 Document type: Article Affiliation country: Ireland

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