Dietary docosahexaenoic acid supplementation prevents age-related functional losses and A2E accumulation in the retina.

Dornstauder, Blake; Suh, Miyoung; Kuny, Sharee; Gaillard, Frédéric; Macdonald, Ian M; Clandinin, Michael T; Sauvé, Yves

Dornstauder, Blake; Suh, Miyoung; Kuny, Sharee; Gaillard, Frédéric; Macdonald, Ian M; Clandinin, Michael T; Sauvé, Yves.

Affiliation

Dornstauder B; Department of Ophthalmology, University of Alberta, Edmonton, Alberta, Canada.

Invest Ophthalmol Vis Sci ; 53(4): 2256-65, 2012 Apr 24.

Article in En | MEDLINE | ID: mdl-22427551

Subject(s)

Aging/physiology; Chromosome Disorders/prevention & control; Dietary Fats, Unsaturated/administration & dosage; Disease Models, Animal; Docosahexaenoic Acids/administration & dosage; Macular Degeneration/prevention & control; Pyridinium Compounds/metabolism; Retina/metabolism; Retinoids/metabolism; Animals; Chromosome Disorders/metabolism; Chromosome Disorders/physiopathology; Chromosomes, Human, Pair 6/metabolism; Dark Adaptation; Electroretinography; Fatty Acids, Omega-3/metabolism; Fatty Acids, Omega-6/metabolism; Female; Fluorescent Antibody Technique, Indirect; Macular Degeneration/congenital; Macular Degeneration/metabolism; Macular Degeneration/physiopathology; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Time Factors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridinium Compounds / Retina / Retinoids / Dietary Fats, Unsaturated / Aging / Docosahexaenoic Acids / Chromosome Disorders / Disease Models, Animal / Macular Degeneration Type of study: Prognostic_studies Limits: Animals Language: En Journal: Invest Ophthalmol Vis Sci Year: 2012 Document type: Article Affiliation country: Canada

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