Inhibition of tumor suppressor protein p53-dependent transcription by a tetramerization domain peptide via hetero-oligomerization.

Wada, Junya; Kamada, Rui; Imagawa, Toshiaki; Chuman, Yoshiro; Sakaguchi, Kazuyasu

Wada, Junya; Kamada, Rui; Imagawa, Toshiaki; Chuman, Yoshiro; Sakaguchi, Kazuyasu.

Affiliation

Wada J; Department of Chemistry, Faculty of Science, Hokkaido University, Kita-ku, Sapporo, Japan.

Bioorg Med Chem Lett ; 22(8): 2780-3, 2012 Apr 15.

Article in En | MEDLINE | ID: mdl-22429466

Subject(s)

Peptides/pharmacology; Protein Multimerization; Transcription, Genetic/drug effects; Tumor Suppressor Protein p53/antagonists & inhibitors; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21/antagonists & inhibitors; Humans; Induced Pluripotent Stem Cells/cytology; Protein Binding; Protein Structure, Tertiary/physiology; Signal Transduction/drug effects; Tumor Suppressor Protein p53/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Transcription, Genetic / Tumor Suppressor Protein p53 / Protein Multimerization Limits: Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2012 Document type: Article Affiliation country: Japan Country of publication: United kingdom

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