Epidemiology of Escherichia coli, Klebsiella species, and Proteus mirabilis strains producing extended-spectrum ß-lactamases from clinical samples in the Kinki Region of Japan.
Am J Clin Pathol
; 137(4): 620-6, 2012 Apr.
Article
in En
| MEDLINE
| ID: mdl-22431539
ABSTRACT
In the present study, nonduplicate, clinical isolates of extended-spectrum ß-lactamase (ESBL)-producing Escherichia coli, Klebsiella spp, and Proteus mirabilis were collected during a 10-year period from 2000 to 2009 at several hospitals in the Kinki region, Japan. The detection rate of E coli markedly increased from 0.24% to 7.25%. The detection rate of Klebsiella pneumoniae increased from 0% to 2.44% and that of P mirabilis from 6.97% to 12.85%. The most frequently detected genotypes were the CTX-M9 group for E coli, the CTX-M2 group for K pneumoniae, and the CTX-M2 group for P mirabilis. E coli clone O25H4-ST131 producing CTX-M-15, which is spreading worldwide, was first detected in 2007. The most common replicon type of E coli was the IncF type, particularly FIB, detected in 466 strains (69.7%). Of the K pneumoniae strains, 47 (55.3%) were of the IncN type; 77 P mirabilis strains (96.3%) were of the IncT type. In the future, the surveillance of various resistant bacteria, mainly ESBL-producing Enterobacteriaceae, should be expanded to prevent their spread.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Proteus Infections
/
Proteus mirabilis
/
Beta-Lactamases
/
Klebsiella Infections
/
Escherichia coli
/
Escherichia coli Infections
/
Klebsiella
Type of study:
Screening_studies
Limits:
Humans
Country/Region as subject:
Asia
Language:
En
Journal:
Am J Clin Pathol
Year:
2012
Document type:
Article
Affiliation country:
Japan