Altered balance of proteolytic isoforms of pro-brain-derived neurotrophic factor in autism.

Garcia, Kristine L P; Yu, Guanhua; Nicolini, Chiara; Michalski, Bernadeta; Garzon, Diego J; Chiu, Victor S; Tongiorgi, Enrico; Szatmari, Peter; Fahnestock, Margaret

Garcia, Kristine L P; Yu, Guanhua; Nicolini, Chiara; Michalski, Bernadeta; Garzon, Diego J; Chiu, Victor S; Tongiorgi, Enrico; Szatmari, Peter; Fahnestock, Margaret.

Affiliation

Garcia KL; Departments of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada.

J Neuropathol Exp Neurol ; 71(4): 289-97, 2012 Apr.

Article in En | MEDLINE | ID: mdl-22437340

Subject(s)

Autistic Disorder/metabolism; Brain-Derived Neurotrophic Factor/metabolism; Protein Precursors/metabolism; Adult; Autistic Disorder/diagnosis; Autistic Disorder/genetics; Brain-Derived Neurotrophic Factor/genetics; Child; Child, Preschool; Female; Humans; Male; Middle Aged; Neuronal Plasticity/genetics; Protein Isoforms/genetics; Protein Isoforms/metabolism; Protein Precursors/genetics; Proteolysis; RNA, Messenger/metabolism; Synapses/genetics; Young Adult

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Precursors / Autistic Disorder / Brain-Derived Neurotrophic Factor Type of study: Diagnostic_studies Limits: Adult / Child / Child, preschool / Female / Humans / Male / Middle aged Language: En Journal: J Neuropathol Exp Neurol Year: 2012 Document type: Article Affiliation country: Canada Country of publication: United kingdom

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