Retrospective analysis of microorganisms isolated from cystic fibrosis patients in Southern Italy, 2002-2010.
J Prev Med Hyg
; 52(4): 209-14, 2011 Dec.
Article
in En
| MEDLINE
| ID: mdl-22442927
ABSTRACT
OBJECTIVE:
This study aim was to determine the prevalence of microorganisms in the respiratory tract of patients with cystic fibrosis (CF) admitted to the CF Reference Centre in Southern Italy between 2002-2010.METHODS:
Microbiology assessment of samples (sputum and tracheal aspirates) collected from patients with pulmonary exacerbation admitted to hospital was carried out. All patients were registered in a database and clinical and microbiological data were retrospectively analysed.RESULTS:
Overall, 188 patients were included and a total of 1217 samples were analysed. The most common microorganisms were Staphylococcus aureus (78.7% of the patients) and Pseudomonas aeruginosa (58%), followed by Candida albicans (19.1%), Haemophilus influenzae (13.3%) and Aspergillus fumigatus (9.6%).CONCLUSION:
Compared to similar studies performed in other European countries, our microbiological data, especially the low occurrence of filamentous fungi, suggest a specific local epidemiology, probably related to some uncommon CFTR mutations, which are specific to Southern Italy.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cystic Fibrosis
/
Mitosporic Fungi
/
Gram-Negative Bacteria
/
Gram-Positive Bacteria
Type of study:
Observational_studies
/
Risk_factors_studies
Limits:
Adolescent
/
Adult
/
Aged
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
/
Middle aged
Country/Region as subject:
Europa
Language:
En
Journal:
J Prev Med Hyg
Journal subject:
SAUDE PUBLICA
Year:
2011
Document type:
Article
Affiliation country:
Italy