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Pyrazolopyrimidines as dual Akt/p70S6K inhibitors.
Rice, Kenneth D; Kim, Moon H; Bussenius, Joerg; Anand, Neel K; Blazey, Charles M; Bowles, Owen J; Canne-Bannen, Lynne; Chan, Diva S-M; Chen, Baili; Co, Erick W; Costanzo, Simona; DeFina, Steven C; Dubenko, Larisa; Engst, Stefan; Franzini, Maurizio; Huang, Ping; Jammalamadaka, Vasu; Khoury, Richard G; Klein, Rhett R; Laird, A Douglas; Le, Donna T; Mac, Morrison B; Matthews, David J; Markby, David; Miller, Nicole; Nuss, John M; Parks, Jason J; Tsang, Tsze H; Tsuhako, Amy L; Wang, Yong; Xu, Wei.
Affiliation
  • Rice KD; Exelixis, 210 E. Grand Avenue, South San Francisco, CA 94080, USA.
Bioorg Med Chem Lett ; 22(8): 2693-7, 2012 Apr 15.
Article in En | MEDLINE | ID: mdl-22450127
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Pyridines / Ribosomal Protein S6 Kinases, 70-kDa / Proto-Oncogene Proteins c-akt Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2012 Document type: Article Affiliation country: United States Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Pyridines / Ribosomal Protein S6 Kinases, 70-kDa / Proto-Oncogene Proteins c-akt Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2012 Document type: Article Affiliation country: United States Country of publication: United kingdom