Inflammation aggravates disease severity in Marfan syndrome patients.

Radonic, Teodora; de Witte, Piet; Groenink, Maarten; de Waard, Vivian; Lutter, Rene; van Eijk, Marco; Jansen, Marnix; Timmermans, Janneke; Kempers, Marlies; Scholte, Arthur J; Hilhorst-Hofstee, Yvonne; van den Berg, Maarten P; van Tintelen, J Peter; Pals, Gerard; Baars, Marieke J H; Mulder, Barbara J M; Zwinderman, Aeilko H

Radonic, Teodora; de Witte, Piet; Groenink, Maarten; de Waard, Vivian; Lutter, Rene; van Eijk, Marco; Jansen, Marnix; Timmermans, Janneke; Kempers, Marlies; Scholte, Arthur J; Hilhorst-Hofstee, Yvonne; van den Berg, Maarten P; van Tintelen, J Peter; Pals, Gerard; Baars, Marieke J H; Mulder, Barbara J M; Zwinderman, Aeilko H.

Affiliation

Radonic T; Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Centre, Amsterdam, The Netherlands.

PLoS One ; 7(3): e32963, 2012.

Article in En | MEDLINE | ID: mdl-22479353

Subject(s)

Inflammation/genetics; Marfan Syndrome/genetics; Oligonucleotide Array Sequence Analysis/methods; Transcriptome; Adolescent; Adult; Aorta/pathology; Cluster Analysis; Cytokines/blood; Dilatation, Pathologic; Female; Gene Expression Profiling; Humans; Inflammation/blood; Inflammation/complications; Male; Marfan Syndrome/blood; Marfan Syndrome/complications; Middle Aged; Severity of Illness Index; Transforming Growth Factor beta/blood; Young Adult

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oligonucleotide Array Sequence Analysis / Transcriptome / Inflammation / Marfan Syndrome Limits: Adolescent / Adult / Female / Humans / Male / Middle aged Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2012 Document type: Article Affiliation country: Netherlands

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