TLR4 and NKT cell synergy in immunotherapy against visceral leishmaniasis.

Karmakar, Subir; Bhaumik, Siddhartha Kumar; Paul, Joydeep; De, Tripti

Karmakar, Subir; Bhaumik, Siddhartha Kumar; Paul, Joydeep; De, Tripti.

Affiliation

Karmakar S; Division of Infectious Disease and Immunology, Indian Institute of Chemical Biology, Council of Scientific and Industrial Research, Kolkata, India.

PLoS Pathog ; 8(4): e1002646, 2012.

Article in En | MEDLINE | ID: mdl-22511870

Subject(s)

Antigen Presentation/drug effects; Antigens, Protozoan/pharmacology; Glycosphingolipids/pharmacology; Immunotherapy/methods; Leishmania donovani/immunology; Leishmaniasis, Visceral/therapy; Natural Killer T-Cells/immunology; Toll-Like Receptor 4/immunology; Animals; Antigen Presentation/genetics; Antigens, CD1d/genetics; Antigens, CD1d/immunology; Antigens, CD1d/metabolism; Antigens, Protozoan/genetics; Antigens, Protozoan/immunology; Antigens, Protozoan/metabolism; Cricetinae; Glycosphingolipids/genetics; Glycosphingolipids/immunology; Glycosphingolipids/metabolism; Leishmania donovani/metabolism; Leishmaniasis, Visceral/genetics; Leishmaniasis, Visceral/immunology; Mice; Mice, Inbred BALB C; Natural Killer T-Cells/metabolism; Polysaccharides/genetics; Polysaccharides/immunology; Polysaccharides/metabolism; Th1 Cells/immunology; Th1 Cells/metabolism; Toll-Like Receptor 4/genetics; Toll-Like Receptor 4/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leishmania donovani / Glycosphingolipids / Antigen Presentation / Toll-Like Receptor 4 / Natural Killer T-Cells / Immunotherapy / Leishmaniasis, Visceral / Antigens, Protozoan Limits: Animals Language: En Journal: PLoS Pathog Year: 2012 Document type: Article Affiliation country: India Country of publication: United States

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