Morphological and functional reversal of phenotypes in a mouse model of Rett syndrome.

Robinson, Lianne; Guy, Jacky; McKay, Leanne; Brockett, Emma; Spike, Rosemary C; Selfridge, Jim; De Sousa, Dina; Merusi, Cara; Riedel, Gernot; Bird, Adrian; Cobb, Stuart R

Robinson, Lianne; Guy, Jacky; McKay, Leanne; Brockett, Emma; Spike, Rosemary C; Selfridge, Jim; De Sousa, Dina; Merusi, Cara; Riedel, Gernot; Bird, Adrian; Cobb, Stuart R.

Affiliation

Robinson L; School of Medical Sciences, University of Aberdeen, Forresterhill, Aberdeen, AB25 2ZD, UK.

Brain ; 135(Pt 9): 2699-710, 2012 Sep.

Article in En | MEDLINE | ID: mdl-22525157

Subject(s)

Behavior, Animal/physiology; Cerebral Cortex/pathology; Methyl-CpG-Binding Protein 2/genetics; Neurons/pathology; Phenotype; Rett Syndrome/genetics; Animals; Cerebral Cortex/metabolism; Cerebral Cortex/physiopathology; Disease Models, Animal; Gene Silencing; Hand Strength/physiology; Humans; Methyl-CpG-Binding Protein 2/metabolism; Mice; Neurons/metabolism; Rett Syndrome/metabolism; Rett Syndrome/pathology; Rett Syndrome/physiopathology; Rotarod Performance Test

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenotype / Behavior, Animal / Rett Syndrome / Cerebral Cortex / Methyl-CpG-Binding Protein 2 / Neurons Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Brain Year: 2012 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom

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