Metachronous brain and intramedullary spinal cord metastases from nonsmall-cell lung cancer: a case report.
Kaohsiung J Med Sci
; 28(5): 289-93, 2012 May.
Article
in En
| MEDLINE
| ID: mdl-22531310
ABSTRACT
A 44-year-old man had a brain tumor secondary to lung adenocarcinoma and underwent craniectomy to remove the brain tumor. After postoperative whole-brain radiation therapy, he underwent pneumonectomy followed by chemotherapy, mediastinal radiotherapy, and target therapy for lung cancer. Thirty-six months after the initial brain surgery, he suffered from neck pain and right upper limb numbness that rapidly progressed to upper extremity weakness and paralysis in 2 months. Magnetic resonance imaging demonstrated an intramedullary spinal cord lesion at the C4 level. Laminectomy and gross intramedullary tumor removal were performed. The patient's neurological function improved after the operation. Nevertheless, 4 months after the intramedullary tumor removal, he began to show multiple metastases. Unfortunately, the patient died from respiratory failure 8 months after diagnosis with intramedullary spinal cord metastasis. In this case, early diagnosis and aggressive surgical treatment combined with postoperative radiotherapy and chemotherapy might have provided this patient with a prolonged survival and better quality of life.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Spinal Cord Neoplasms
/
Brain Neoplasms
/
Carcinoma, Non-Small-Cell Lung
/
Lung Neoplasms
Type of study:
Screening_studies
Aspects:
Patient_preference
Limits:
Adult
/
Humans
/
Male
Language:
En
Journal:
Kaohsiung J Med Sci
Journal subject:
MEDICINA
Year:
2012
Document type:
Article
Affiliation country:
Taiwan