Ca(2+)-dependent desensitization of insulin secretion by strong potassium depolarization.

Willenborg, M; Belz, M; Schumacher, K; Paufler, A; Hatlapatka, K; Rustenbeck, I

Willenborg, M; Belz, M; Schumacher, K; Paufler, A; Hatlapatka, K; Rustenbeck, I.

Affiliation

Willenborg M; Institute of Pharmacology and Toxicology, University of Braunschweig, Braunschweig, Germany.

Am J Physiol Endocrinol Metab ; 303(2): E223-33, 2012 Jul 15.

Article in En | MEDLINE | ID: mdl-22550068

Subject(s)

Calcium/metabolism; Insulin/metabolism; Islets of Langerhans/metabolism; Potassium/pharmacology; Animals; Choline/pharmacology; Hypoglycemic Agents/pharmacology; Insulin Secretion; Islets of Langerhans/drug effects; Lipotropic Agents/pharmacology; Mannitol/pharmacology; Membrane Potentials/drug effects; Membrane Potentials/physiology; Mice; Sodium Chloride/pharmacology; Tolbutamide/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Potassium / Calcium / Islets of Langerhans / Insulin Limits: Animals Language: En Journal: Am J Physiol Endocrinol Metab Journal subject: ENDOCRINOLOGIA / FISIOLOGIA / METABOLISMO Year: 2012 Document type: Article Affiliation country: Germany Country of publication: United States

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