Efficacy and toxicity of intravenous iron in a mouse model of critical care anemia*.

Heming, Nicholas; Lettéron, Philippe; Driss, Fathi; Millot, Sarah; El Benna, Jamel; Tourret, Jérome; Denamur, Erick; Montravers, Philippe; Beaumont, Carole; Lasocki, Sigismond

Heming, Nicholas; Lettéron, Philippe; Driss, Fathi; Millot, Sarah; El Benna, Jamel; Tourret, Jérome; Denamur, Erick; Montravers, Philippe; Beaumont, Carole; Lasocki, Sigismond.

Affiliation

Heming N; INSERM U773, Univ Paris Diderot, Sorbonne Paris Cité, Site Bichat, Paris, France.

Crit Care Med ; 40(7): 2141-8, 2012 Jul.

Article in En | MEDLINE | ID: mdl-22564959

Subject(s)

Anemia/drug therapy; Ferric Compounds/administration & dosage; Ferric Compounds/toxicity; Hematinics/administration & dosage; Hematinics/toxicity; Maltose/analogs & derivatives; Animals; Antimicrobial Cationic Peptides/genetics; Antimicrobial Cationic Peptides/metabolism; Catalase/genetics; Catalase/metabolism; Diet; Disease Models, Animal; Hemoglobins; Hepcidins; Inflammation/chemically induced; Injections, Intravenous; Iron/administration & dosage; Iron/analysis; Liver/chemistry; Liver/metabolism; Luminescence; Maltose/administration & dosage; Maltose/toxicity; Mice; Mice, Inbred C57BL; Phlebotomy; RNA, Messenger/metabolism; Random Allocation; Reactive Oxygen Species/blood; Sepsis/drug therapy; Spleen/chemistry; Superoxide Dismutase/genetics; Superoxide Dismutase/metabolism; Trace Elements/administration & dosage; Zymosan/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ferric Compounds / Hematinics / Anemia / Maltose Limits: Animals Language: En Journal: Crit Care Med Year: 2012 Document type: Article Affiliation country: France Country of publication: United States

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