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Identification of imidazo-pyrrolopyridines as novel and potent JAK1 inhibitors.
Kulagowski, Janusz J; Blair, Wade; Bull, Richard J; Chang, Christine; Deshmukh, Gauri; Dyke, Hazel J; Eigenbrot, Charles; Ghilardi, Nico; Gibbons, Paul; Harrison, Trevor K; Hewitt, Peter R; Liimatta, Marya; Hurley, Christopher A; Johnson, Adam; Johnson, Tony; Kenny, Jane R; Bir Kohli, Pawan; Maxey, Robert J; Mendonca, Rohan; Mortara, Kyle; Murray, Jeremy; Narukulla, Raman; Shia, Steven; Steffek, Micah; Ubhayakar, Savita; Ultsch, Mark; van Abbema, Anne; Ward, Stuart I; Waszkowycz, Bohdan; Zak, Mark.
Affiliation
  • Kulagowski JJ; Department of Medicinal Chemistry, Argenta, 8/9 Spire Green Centre, Harlow CM19 5TR, United Kingdom. janusz.kulagowski@glpg
J Med Chem ; 55(12): 5901-21, 2012 Jun 28.
Article in En | MEDLINE | ID: mdl-22591402
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Protein Kinase Inhibitors / Janus Kinase 1 / Imidazoles Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2012 Document type: Article Affiliation country: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Protein Kinase Inhibitors / Janus Kinase 1 / Imidazoles Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2012 Document type: Article Affiliation country: United kingdom