Neonatal lupus erythematosus and its clinical variability.
J Dtsch Dermatol Ges
; 10(6): 407-11, 2012 Jun.
Article
in En, De
| MEDLINE
| ID: mdl-22606966
ABSTRACT
Neonatal lupus erythematosus (NLE) is a rare disease affecting newborns that is caused by maternal autoantibodies transmitted across the placenta. The disease may affect the skin, the heart, and rarely the hepatobiliary or hematological systems. A serious complication affecting some patients with NLE is atrioventricular heart block (AV block). The clinical picture of cutaneous NLE varies considerably. NLE presents with confluent, scaly, periorbital erythema, or erythematous infiltrated plaques with central vesicles and lesions resembling seborrheic eczema or fungal infection. In any newborn with such skin lesions, NLE should be included in the differential diagnosis. Dermatologists play an important role in the diagnosis. We review different skin lesions occurring in neonatal lupus erythematosus based on five patients from our own clinic.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Lupus Erythematosus, Systemic
Type of study:
Diagnostic_studies
Limits:
Female
/
Humans
/
Male
/
Newborn
Language:
De
/
En
Journal:
J Dtsch Dermatol Ges
Journal subject:
DERMATOLOGIA
Year:
2012
Document type:
Article
Affiliation country:
Austria
Publication country:
ALEMANHA
/
ALEMANIA
/
DE
/
DEUSTCHLAND
/
GERMANY