Depolarization potentiates TRAIL-induced apoptosis in human melanoma cells: role for ATP-sensitive K+ channels and endoplasmic reticulum stress.

Suzuki, Yoshihiro; Inoue, Toshio; Murai, Mayumi; Suzuki-Karasaki, Miki; Ochiai, Toyoko; Ra, Chisei

Suzuki, Yoshihiro; Inoue, Toshio; Murai, Mayumi; Suzuki-Karasaki, Miki; Ochiai, Toyoko; Ra, Chisei.

Affiliation

Suzuki Y; Nihon University Graduate School of Medical Science, Tokyo, Japan. suzuki.yoshihiro@nihon-u.ac.jp

Int J Oncol ; 41(2): 465-75, 2012 Aug.

Article in En | MEDLINE | ID: mdl-22613960

Subject(s)

Antineoplastic Agents/pharmacology; Apoptosis/drug effects; Endoplasmic Reticulum Stress; KATP Channels/metabolism; TNF-Related Apoptosis-Inducing Ligand/pharmacology; Adamantane/analogs & derivatives; Adamantane/pharmacology; Caspase 12/metabolism; Caspase 3/metabolism; Caspase 7/metabolism; Enzyme Activation; Glyburide/pharmacology; Humans; KATP Channels/antagonists & inhibitors; Melanocytes/drug effects; Melanoma; Membrane Potential, Mitochondrial/drug effects; Membrane Potentials/drug effects; Morpholines/pharmacology; Potassium/metabolism; Potassium/physiology; Potassium Channel Blockers/pharmacology; Tumor Cells, Cultured

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Apoptosis / TNF-Related Apoptosis-Inducing Ligand / KATP Channels / Endoplasmic Reticulum Stress / Antineoplastic Agents Type of study: Diagnostic_studies Limits: Humans Language: En Journal: Int J Oncol Journal subject: NEOPLASIAS Year: 2012 Document type: Article Affiliation country: Japan Country of publication: Greece

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