Morphological and pathological evolution of the brain microcirculation in aging and Alzheimer's disease.

Hunter, Jesse M; Kwan, Jason; Malek-Ahmadi, Michael; Maarouf, Chera L; Kokjohn, Tyler A; Belden, Christine; Sabbagh, Marwan N; Beach, Thomas G; Roher, Alex E

Hunter, Jesse M; Kwan, Jason; Malek-Ahmadi, Michael; Maarouf, Chera L; Kokjohn, Tyler A; Belden, Christine; Sabbagh, Marwan N; Beach, Thomas G; Roher, Alex E.

Affiliation

Hunter JM; The Longtine Center for Neurodegenerative Biochemistry, Banner Sun Health Research Institute, Sun City, Arizona, United States of America.

PLoS One ; 7(5): e36893, 2012.

Article in En | MEDLINE | ID: mdl-22615835

Subject(s)

Aging/pathology; Alzheimer Disease/pathology; Brain/blood supply; Microvessels/pathology; Aged; Aged, 80 and over; Aging/metabolism; Alzheimer Disease/metabolism; Apolipoprotein E4/metabolism; Capillaries/metabolism; Capillaries/pathology; Cerebral Cortex/metabolism; Cerebral Cortex/pathology; Cholinergic Neurons/metabolism; Cholinergic Neurons/pathology; Cohort Studies; Dementia/metabolism; Dementia/pathology; Female; Humans; Immunohistochemistry/methods; Male; Microcirculation; Microvessels/metabolism; Neurons, Afferent/metabolism; Neurons, Afferent/pathology; Plaque, Amyloid/metabolism; Plaque, Amyloid/pathology; Tyrosine 3-Monooxygenase/metabolism; Vasoconstriction/physiology; Vasodilation/physiology; Vesicular Acetylcholine Transport Proteins/metabolism

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain / Aging / Microvessels / Alzheimer Disease Type of study: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limits: Aged / Aged80 / Female / Humans / Male Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2012 Document type: Article Affiliation country: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google