Improving thermal stability and efficacy of BCNU in treating glioma cells using PAA-functionalized graphene oxide.

Lu, Yu-Jen; Yang, Hung-Wei; Hung, Sheng-Che; Huang, Chiung-Yin; Li, Shin-Ming; Ma, Chen-Chi M; Chen, Pin-Yuan; Tsai, Hong-Chieh; Wei, Kuo-Chen; Chen, Jyh-Ping

Lu, Yu-Jen; Yang, Hung-Wei; Hung, Sheng-Che; Huang, Chiung-Yin; Li, Shin-Ming; Ma, Chen-Chi M; Chen, Pin-Yuan; Tsai, Hong-Chieh; Wei, Kuo-Chen; Chen, Jyh-Ping.

Affiliation

Lu YJ; Department of Chemical and Materials Engineering, Chang Gung University, Kwei-San, Taoyuan, Taiwan.

Int J Nanomedicine ; 7: 1737-47, 2012.

Article in En | MEDLINE | ID: mdl-22619524

Subject(s)

Antineoplastic Agents, Alkylating/administration & dosage; Carmustine/administration & dosage; Glioma/drug therapy; Acrylic Resins/chemistry; Animals; Antineoplastic Agents, Alkylating/pharmacokinetics; Carmustine/pharmacokinetics; Cell Line, Tumor; Drug Carriers/chemistry; Drug Delivery Systems; Drug Stability; Endocytosis; Glioma/metabolism; Glioma/ultrastructure; Graphite/chemistry; Half-Life; Mice; Microscopy, Atomic Force; Microscopy, Electron, Transmission; Nanoconjugates/chemistry; Nanoconjugates/ultrastructure; Nanomedicine; Temperature

Key words

BCNU; drug delivery; glioma cells; graphene oxide; thermal stability

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carmustine / Antineoplastic Agents, Alkylating / Glioma Limits: Animals Language: En Journal: Int J Nanomedicine Year: 2012 Document type: Article Affiliation country: Taiwan Country of publication: New Zealand

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