Orthobunyavirus entry into neurons and other mammalian cells occurs via clathrin-mediated endocytosis and requires trafficking into early endosomes.

Hollidge, Bradley S; Nedelsky, Natalia B; Salzano, Mary-Virginia; Fraser, Jonathan W; González-Scarano, Francisco; Soldan, Samantha S

Hollidge, Bradley S; Nedelsky, Natalia B; Salzano, Mary-Virginia; Fraser, Jonathan W; González-Scarano, Francisco; Soldan, Samantha S.

Affiliation

Hollidge BS; Department of Neurology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.

J Virol ; 86(15): 7988-8001, 2012 Aug.

Article in En | MEDLINE | ID: mdl-22623766

Subject(s)

Clathrin/metabolism; Encephalitis, California/metabolism; Endocytosis; Endosomes/metabolism; La Crosse virus/metabolism; Virus Internalization; Animals; Chlorocebus aethiops; Clathrin/genetics; Cricetinae; Encephalitis, California/drug therapy; Encephalitis, California/genetics; Endosomes/genetics; Endosomes/virology; HeLa Cells; Humans; La Crosse virus/genetics; Vero Cells; rab GTP-Binding Proteins/genetics; rab GTP-Binding Proteins/metabolism; rab5 GTP-Binding Proteins/genetics; rab5 GTP-Binding Proteins/metabolism; rab7 GTP-Binding Proteins

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Endosomes / Clathrin / La Crosse virus / Encephalitis, California / Endocytosis / Virus Internalization Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Virol Year: 2012 Document type: Article Affiliation country: United States

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