Benzenesulfonates/therapeutic use; Carcinoma, Hepatocellular/drug therapy; Liver Neoplasms/drug therapy; Protein Kinase Inhibitors/therapeutic use; Pyridines/therapeutic use; Quinazolines/therapeutic use; Animals; Apoptosis/drug effects; Benzenesulfonates/pharmacology; Carcinoma, Hepatocellular/metabolism; Cell Movement/drug effects; Cell Survival/drug effects; Drug Therapy, Combination; Endothelial Cells/drug effects; Endothelial Cells/metabolism; ErbB Receptors/metabolism; Erlotinib Hydrochloride; Hep G2 Cells; Humans; Liver Neoplasms/metabolism; Neoplasm Transplantation; Neovascularization, Pathologic/metabolism; Niacinamide/analogs & derivatives; Phenylurea Compounds; Protein Kinase Inhibitors/pharmacology; Pyridines/pharmacology; Quinazolines/pharmacology; RNA, Messenger/metabolism; Rats; Sorafenib; Vascular Endothelial Growth Factor A/drug effects; Vascular Endothelial Growth Factor A/genetics; Vascular Endothelial Growth Factor A/metabolism