Inhibition of Epstein-Barr virus reactivation in nasopharyngeal carcinoma cells by dietary sulforaphane.

Wu, Chung-Chun; Chuang, Hsin-Ying; Lin, Chao-Yi; Chen, Yen-Ju; Tsai, Wan-Hua; Fang, Chih-Yeu; Huang, Sheng-Yen; Chuang, Fu-Yang; Lin, Su-Fang; Chang, Yao; Chen, Jen-Yang

Wu, Chung-Chun; Chuang, Hsin-Ying; Lin, Chao-Yi; Chen, Yen-Ju; Tsai, Wan-Hua; Fang, Chih-Yeu; Huang, Sheng-Yen; Chuang, Fu-Yang; Lin, Su-Fang; Chang, Yao; Chen, Jen-Yang.

Affiliation

Wu CC; National Institute of Cancer Research, National Health Research Institutes, Zhunan, Taiwan.

Mol Carcinog ; 52(12): 946-58, 2013 Dec.

Article in En | MEDLINE | ID: mdl-22641235

Subject(s)

Herpesvirus 4, Human/drug effects; Isothiocyanates/pharmacology; Nasopharyngeal Neoplasms/virology; Antiviral Agents/pharmacology; Carcinoma; Dietary Supplements; Epithelial Cells/drug effects; Epithelial Cells/virology; Epstein-Barr Virus Infections/drug therapy; Epstein-Barr Virus Infections/prevention & control; Epstein-Barr Virus Infections/virology; Gene Expression Regulation, Viral/drug effects; Genes, Immediate-Early; Herpesvirus 4, Human/pathogenicity; Herpesvirus 4, Human/physiology; Histone Deacetylase Inhibitors/pharmacology; Humans; Immediate-Early Proteins/genetics; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms/drug therapy; Promoter Regions, Genetic; Sulfoxides; Trans-Activators/genetics; Trans-Activators/metabolism; Tumor Cells, Cultured; Virus Activation/drug effects

Key words

Epstein-Barr virus; histone deacetylase inhibitor; lytic cycle; reactivation; sulforaphane

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nasopharyngeal Neoplasms / Isothiocyanates / Herpesvirus 4, Human Limits: Humans Language: En Journal: Mol Carcinog Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2013 Document type: Article Affiliation country: Taiwan Country of publication: United States

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