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Design and synthesis of a novel series of bicyclic heterocycles as potent γ-secretase modulators.
Bischoff, Francois; Berthelot, Didier; De Cleyn, Michel; Macdonald, Gregor; Minne, Garrett; Oehlrich, Daniel; Pieters, Serge; Surkyn, Michel; Trabanco, Andrés A; Tresadern, Gary; Van Brandt, Sven; Velter, Ingrid; Zaja, Mirko; Borghys, Herman; Masungi, Chantal; Mercken, Marc; Gijsen, Harrie J M.
Affiliation
  • Bischoff F; Janssen Research & Development, Pharmaceutical Companies of Johnson & Johnson, Beerse, Belgium.
J Med Chem ; 55(21): 9089-106, 2012 Nov 08.
Article in En | MEDLINE | ID: mdl-22650177
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzimidazoles / Bridged Bicyclo Compounds, Heterocyclic / Amyloid Precursor Protein Secretases / Imidazoles Limits: Animals / Humans / Male Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2012 Document type: Article Affiliation country: Belgium Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzimidazoles / Bridged Bicyclo Compounds, Heterocyclic / Amyloid Precursor Protein Secretases / Imidazoles Limits: Animals / Humans / Male Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2012 Document type: Article Affiliation country: Belgium Country of publication: United States