C/EBP homologous protein contributes to cytokine-induced pro-inflammatory responses and apoptosis in ß-cells.

Allagnat, F; Fukaya, M; Nogueira, T C; Delaroche, D; Welsh, N; Marselli, L; Marchetti, P; Haefliger, J A; Eizirik, D L; Cardozo, A K

Allagnat, F; Fukaya, M; Nogueira, T C; Delaroche, D; Welsh, N; Marselli, L; Marchetti, P; Haefliger, J A; Eizirik, D L; Cardozo, A K.

Affiliation

Allagnat F; Laboratoire de Médecine Expérimentale, Université Libre de Bruxelles, Brussels, Belgium.

Cell Death Differ ; 19(11): 1836-46, 2012 Nov.

Article in En | MEDLINE | ID: mdl-22653339

Subject(s)

Apoptosis/drug effects; Cytokines/pharmacology; Insulin-Secreting Cells/metabolism; Transcription Factor CHOP/metabolism; Animals; Caspase 3/metabolism; Caspase 9/metabolism; Cell Line; Cell Nucleus/metabolism; Diabetes Mellitus, Type 1/metabolism; Diabetes Mellitus, Type 1/pathology; Endoplasmic Reticulum Stress; I-kappa B Kinase/metabolism; Insulin-Secreting Cells/cytology; Interferon-gamma/pharmacology; Interleukin-1beta/pharmacology; Mitochondria/metabolism; Myeloid Cell Leukemia Sequence 1 Protein; NF-kappa B/metabolism; Proto-Oncogene Proteins c-bcl-2/metabolism; Rats; Transcription Factor CHOP/antagonists & inhibitors; Transcription Factor CHOP/genetics; Transcription Factor RelA/metabolism; Tumor Necrosis Factor-alpha/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cytokines / Apoptosis / Insulin-Secreting Cells / Transcription Factor CHOP Limits: Animals Language: En Journal: Cell Death Differ Year: 2012 Document type: Article Affiliation country: Belgium Country of publication: United kingdom

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