Inorganic arsenic impairs proliferation and cytokine expression in human primary T lymphocytes.

Morzadec, Claudie; Bouezzedine, Fidaa; Macoch, Mélinda; Fardel, Olivier; Vernhet, Laurent

Morzadec, Claudie; Bouezzedine, Fidaa; Macoch, Mélinda; Fardel, Olivier; Vernhet, Laurent.

Affiliation

Morzadec C; UMR INSERM U1085, Institut de Recherche sur la Santé, l'Environnement et le Travail (IRSET), Université de Rennes 1, 2 avenue du Professeur Léon Bernard, 35043 Rennes, France.

Toxicology ; 300(1-2): 46-56, 2012 Oct 09.

Article in En | MEDLINE | ID: mdl-22683347

Subject(s)

Arsenicals/adverse effects; Cell Proliferation/drug effects; Cytokines/biosynthesis; T-Lymphocytes/drug effects; Arsenites/adverse effects; Cyclin D3/analysis; Cyclin D3/biosynthesis; Cytokines/analysis; Flow Cytometry; G1 Phase/drug effects; Humans; Interferon-gamma/analysis; Interferon-gamma/biosynthesis; Interleukin-13/analysis; Interleukin-13/biosynthesis; Interleukin-2/analysis; Interleukin-2/biosynthesis; Interleukin-4/analysis; Interleukin-4/biosynthesis; Lymphocyte Activation/drug effects; Reactive Oxygen Species/analysis; Real-Time Polymerase Chain Reaction; Sodium Compounds/adverse effects; T-Lymphocytes/chemistry; T-Lymphocytes/metabolism; T-Lymphocytes/physiology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arsenicals / T-Lymphocytes / Cytokines / Cell Proliferation Limits: Humans Language: En Journal: Toxicology Year: 2012 Document type: Article Affiliation country: France Country of publication: Ireland

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