Enantioselective synthesis of a dual orexin receptor antagonist.

Mangion, Ian K; Sherry, Benjamin D; Yin, Jingjun; Fleitz, Fred J

Mangion, Ian K; Sherry, Benjamin D; Yin, Jingjun; Fleitz, Fred J.

Affiliation

Mangion IK; Department of Process Research, Merck and Co., Inc., P.O. Box 2000, Rahway, New Jersey 07065, USA. ian_mangion@merck.com

Org Lett ; 14(13): 3458-61, 2012 Jul 06.

Article in En | MEDLINE | ID: mdl-22725839

Subject(s)

Azepines/chemical synthesis; Triazoles/chemical synthesis; Azepines/chemistry; Azepines/pharmacology; Molecular Structure; Orexin Receptors; Receptors, G-Protein-Coupled/antagonists & inhibitors; Receptors, Neuropeptide/antagonists & inhibitors; Stereoisomerism; Structure-Activity Relationship; Triazoles/chemistry; Triazoles/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Azepines / Triazoles Language: En Journal: Org Lett Journal subject: BIOQUIMICA Year: 2012 Document type: Article Affiliation country: United States Country of publication: United States

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