Biophysical mechanism of T-cell receptor triggering in a reconstituted system.

James, John R; Vale, Ronald D

James, John R; Vale, Ronald D.

Affiliation

James JR; Howard Hughes Medical Institute and Department of Cellular and Molecular Pharmacology, University of California, San Francisco, 600 16th Street, San Francisco, California 94158, USA.

Nature ; 487(7405): 64-9, 2012 Jul 05.

Article in En | MEDLINE | ID: mdl-22763440

Subject(s)

Cell Transdifferentiation/genetics; Genetic Engineering; Lymphocyte Activation/immunology; Receptors, Antigen, T-Cell/metabolism; Synthetic Biology/methods; T-Lymphocytes/metabolism; Transduction, Genetic; Antigen-Presenting Cells/immunology; Antigen-Presenting Cells/metabolism; Cell Compartmentation; Cell Membrane/enzymology; HEK293 Cells; Histocompatibility Antigens Class II/immunology; Histocompatibility Antigens Class II/metabolism; Humans; Leukocyte Common Antigens/genetics; Leukocyte Common Antigens/metabolism; Lymphocyte Specific Protein Tyrosine Kinase p56(lck)/metabolism; Phosphorylation; Receptors, Antigen, T-Cell/immunology; Signal Transduction/immunology; T-Lymphocytes/enzymology; T-Lymphocytes/immunology; Time Factors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transduction, Genetic / Lymphocyte Activation / Receptors, Antigen, T-Cell / T-Lymphocytes / Genetic Engineering / Cell Transdifferentiation / Synthetic Biology Limits: Humans Language: En Journal: Nature Year: 2012 Document type: Article Affiliation country: United States Country of publication: United kingdom

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