Differential mechanisms of action are involved in chlorpyrifos effects in estrogen-dependent or -independent breast cancer cells exposed to low or high concentrations of the pesticide.

Ventura, Clara; Núñez, Mariel; Miret, Noelia; Martinel Lamas, Diego; Randi, Andrea; Venturino, Andrés; Rivera, Elena; Cocca, Claudia

Ventura, Clara; Núñez, Mariel; Miret, Noelia; Martinel Lamas, Diego; Randi, Andrea; Venturino, Andrés; Rivera, Elena; Cocca, Claudia.

Affiliation

Ventura C; Laboratorio de Radioisótopos, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Argentina.

Toxicol Lett ; 213(2): 184-93, 2012 Sep 03.

Article in En | MEDLINE | ID: mdl-22771950

Subject(s)

Breast Neoplasms/chemically induced; Chlorpyrifos/toxicity; Estrogen Receptor alpha/metabolism; Insecticides/toxicity; Neoplasms, Hormone-Dependent/chemically induced; Blotting, Western; Breast Neoplasms/metabolism; Breast Neoplasms/pathology; Cell Cycle/drug effects; Cell Line, Tumor; Cell Proliferation/drug effects; Cyclins/metabolism; Female; Flow Cytometry; Humans; MCF-7 Cells; Neoplasms, Hormone-Dependent/metabolism; Neoplasms, Hormone-Dependent/pathology; Oxidation-Reduction; Phosphorylation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Estrogen Receptor alpha / Chlorpyrifos / Insecticides / Neoplasms, Hormone-Dependent Type of study: Risk_factors_studies Limits: Female / Humans Language: En Journal: Toxicol Lett Year: 2012 Document type: Article Affiliation country: Argentina Country of publication: Netherlands

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