Role of PARP inhibitors in cancer biology and therapy.

Davar, D; Beumer, J H; Hamieh, L; Tawbi, H

Davar, D; Beumer, J H; Hamieh, L; Tawbi, H.

Affiliation

Davar D; Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.

Curr Med Chem ; 19(23): 3907-21, 2012.

Article in En | MEDLINE | ID: mdl-22788767

Subject(s)

Enzyme Inhibitors/therapeutic use; Neoplasms/drug therapy; Poly(ADP-ribose) Polymerase Inhibitors; BRCA1 Protein/genetics; BRCA1 Protein/metabolism; BRCA2 Protein/genetics; BRCA2 Protein/metabolism; Clinical Trials as Topic; DNA Repair; Drug Resistance, Neoplasm; Humans; Neoplasms/metabolism; Poly(ADP-ribose) Polymerases/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Enzyme Inhibitors / Poly(ADP-ribose) Polymerase Inhibitors / Neoplasms Limits: Humans Language: En Journal: Curr Med Chem Journal subject: QUIMICA Year: 2012 Document type: Article Affiliation country: United States

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